Modeling and estimation of production rate for the production phase of non-growth associated high cell density processes
Title | Modeling and estimation of production rate for the production phase of non-growth associated high cell density processes |
Publication Type | Journal Article |
Year of Publication | 2015 |
Authors | Jamilis M, Garelli F, Mozumder MSI, CastaƱeda T, De Battista H |
Journal | Bioprocess and Biosystems Engineering |
Volume | 38 |
Pagination | 1903-1914 |
Keywords | Bioplastics, Estimation, high cell density, Observer, PHB, Sliding mode, Software sensor, volume model |
Abstract | This paper addresses the estimation of the specific production rate of intracellular products and the modeling of the bioreactor volume dynamics in high cell density fed-batch reactors. |
DOI | 10.1007/s00449-015-1430-7 |